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J Korean Soc Emerg Med > Volume 13(3); 2002 > Article
Journal of The Korean Society of Emergency Medicine 2002;13(3): 351-353.
Childhood Ischemic Stroke Associated with Protein S Deficiency: A case report
Yeon Ho You, Seong Soo Park, Jung Gyu Park, Jung Soo Park, Sung Pil Chung
Department of Emergency Medicine, Chungnam National University Hospital, Daejeon, Korea. cpr@chollian.net
ABSTRACT
The occurrence of acute ischemic stroke in childhood is rare. The etiology of childhood ischemic stroke is different from that of an adult, and coagulation abnormalities are suspected to be related. Protein S is a vitamin-K-dependent plasma protein that inhibits the coagulation system by serving as a cofactor for activated protein C, and the clinical manifestations of its deficiency are virtually identical to those of protein C deficiency. We reported the case of a child who presented with right side weakness and who was diagnosed as having a cerebral infarction associated with protein S deficiency as the cause of stroke.
Key words: Cerebral infarction, Protein S deficiency
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