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J Korean Soc Emerg Med > Volume 28(1); 2017 > Article
Journal of The Korean Society of Emergency Medicine 2017;28(1): 32-39.
대기 중 미세먼지 농도와 응급실을 방문하는 만성 폐쇄성 폐 질환 환자와의 상관관계
오지수1, 박상현1, 곽명관1, 표창해1, 박근홍1, 김한범1, 신승열1, 최한조2
1서울특별시 서울의료원 응급의학과
2삼성서울병원 응급의학과
Ambient Particulate Matter and Emergency Department Visit for Chronic Obstructive Pulmonary Disease
Ji Su Oh1, Sang Hyun Park1, Myoung Kwan Kwak1, Chang Hae Pyo1, Keun Hong Park1, Hahn Bom Kim1, Seoung Yul Shin1, Han Jo Choi2
1Department of Emergency Medicine, Seoul Medical Center, Seoul, Korea
2Department of Emergency Medicine, Samsung Medical Center, Seoul, Korea
Correspondence  Sang Hyun Park ,Tel: 02-2276-7424, Fax: 02-2276-7418, Email: emergency70@hanmail.net ,
Received: August 30, 2016; Revised: September 2, 2016   Accepted: October 23, 2016.  Published online: February 28, 2017.
ABSTRACT
Purpose:
This study aimed to explore the association between increased level of ambient particulate matter and emergency room visits for chronic obstructive pulmonary disease (COPD) exacerbations.
Method:
A retrospective study was conducted. We enrolled patients who lived in Seoul, Korea and were diagnosed with COPD in the emergency room between January 2012 and December 2014. Meteorological factors [daily highest temperature, lowest temperature, mean temperature, diurnal temperature, rainfall, relative humidity, amount of sunshine and particulate matter less than 10 μm (PM 10)] between December 2011 and December 2014 in Seoul were acquired from the Korea Meteorological Administration. We used a multiple Poisson regression model with daily patient’s number of COPD as a response variable and meteorological factors as explanatory variable. Variable selection was done via an Elastic net.
Results:
There was a total of 1,179 emergency visits for acute exacerbations of COPD patients. PM10 (before 4, 10, 11, 15, 16, 17, 22, 24, 27, 28 day), rainfall (before 1, 6, 8, 16, 18 day), relative humidity (before 2, 8), and daily temperature difference (5, 10, 15 day) had a relationship and a lag effect with COPD exacerbations.
Conclusion:
This study showed that an increased concentration of PM10 was associated with COPD exacerbations. A future study that reinforces the limitation of this study is necessary to get a helpful index for an adequate response of medical institution and efficient placement of medical personnel.
Key words: Pulmonary disease, Chronic obstructive, Particulate matter, Regression analysis
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