| 병원 전 심정지 후 자발순환이 회복된 환자에서 치료적 저체온 요법을 시행하는데 있어 치료온도까지 도달하는데 영향을 주는 인자 분석 |
| 유재진1, 김진주1, 황인철2, 조진성1, 임용수1, 양혁준1, 이근1 |
1가천대 길병원 응급의학교실
2가천대 길병원 가정의학과 |
| The Analysis of Factors Related to Reaching to Therapeutic Range in Patients with Receiving Therapeutic Hypothermia after Return of Spontaneous Circulation after Out-of hospital Cardiac Arrest |
| Jae Jin Ryou1, Jin Joo Kim1, In Cheol Hwang2, Jin Seong Cho1, Yong Su Lim1, Hyuk Jun Yang1, Keun Lee1 |
1Department of Emergency Medicine, Gachon University Gil Medical Center, Incheon, Korea
2Department of Family Medicine, Gachon University Gil Medical Center, Incheon, Korea |
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Received: June 24, 2015; Revised: June 25, 2015 Accepted: October 1, 2015. Published online: December 30, 2015. |
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| ABSTRACT |
Purpose:
The relationship between prognostic factors and outcomes of post-cardiac arrest patients treated with therapeutic hypothermia was analyzed.
Method:
We conducted a tertiary center retrospective study of post-cardiac arrest patients treated with therapeutic hypothermia between January 2008 and December 2012. We investigated the association of the following factors with outcomes: BMI, time to ROSC, number of vasoactive drugs, smoking, alcohol, and short time to therapeutic range in hypothermia.
Results:
A total of 251 patients were enrolled in this study. Large number of vasoactive drugs was a prognostic factor of 3-month mortality (adjusted OR 1.96, 95% CI:1.41-2.71, p<0.001). Obesity (BMI≥25 kg/m2) was not associated with delayed time to therapeutic range in hypothermia. Both univariate and multivariate analysis showed that high initial BT (β(SE)=63.64 (11.53), p<0.001) and a small number of vasoactive drugs (β(SE)=18.66(8.74), p=0.034) were independent predictors of delayed time to therapeutic range in hypothermia.
Conclusion:
In this study, a small number of vasoactive drugs showed a significant influence on delayed time to therapeutic range in patients receiving therapeutic hypothermia after return of spontaneous circulation after out-of-hospital cardiac arrest. |
| Key words:
Induced hypothermia, Heart arrest, Vasoactive drug, Outcome |
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