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J Korean Soc Emerg Med > Volume 32(1); 2021 > Article
Journal of The Korean Society of Emergency Medicine 2021;32(1): 19-26.
증상 발현 후 6시간 이내 응급실 도착한 급성심근경색증에서 hs-CRP 및 CRP velocity와 재원 기간 내 단기 예후와의 상관 관계
박진원 , 조태진 , 곽세정 , 윤성현
가톨릭관동대학교 국제성모병원 응급의학과
Correlation between hs-CRP and CRP velocity and in-hospital short term prognosis in acute myocardial infarction, which arrived in the ER within 6 hours after symptoms are expressed
Jin Won Park , Tae Jin Cho , Sae Jeung Kwak , Sung Hyun Yun
Department of Emergency Medicine, Catholic Kwandong University International St. Mary’s Hospital, Incheon, Korea
Correspondence  Sung Hyun Yun ,Tel: 032-290-3030, Fax: 032-290-2886, Email: jimin0415@ish.ac.kr,
Received: February 17, 2020; Revised: May 13, 2020   Accepted: July 17, 2020.  Published online: February 26, 2021.
ABSTRACT
Objective:
This study is to measure the high sensitivity C-reactive protein (hs-CRP) value in acute myocardial infarction (AMI) patients who arrive within 6 hours of the symptom manifestation and see how the resulting value affects the short term prognosis in AMI patients.
Method:
This study was conducted on 118 patients who had less than 6 hours of onset-to-door time among 149 patients who were diagnosed with myocardial infarction in emergency room and undergo percutaneous coronary intervention (PCI) for 2 years from September 2017. The group including main adverse cardiovascular outcomes were compared in the patients according to the blood test figures (hs-CRP on admission [CRP1], CRP velocity [CRPv], post-PCI hs-CRP [CRP2], and CRP difference values [CRP2-1]).
Results:
In this study, the average of the hs-CRP values of AMI patients arriving within 6 hours of the symptom manifestation was 2.2±2.3 mg/L. CRP velocity that corrected the CRP value to the elapsed time after the onset of symptoms and N-terminal probrain natriuretic peptide (NT-proBNP) appeared to be significantly correlated with the occurrence of main adverse cardiovascular outcomes (P=0.03).
Conclusion:
The hs-CRP values of AMI patients arrived within 6 hours of the symptom manifestation showed the mean risk group. CRPv and NT-proBNP showed a significant casual relationship with main adverse cardiovascular outcomes.
Key words: hs-CRP; Velocity; Acute myocardial infarction
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