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Journal of The Korean Society of Emergency Medicine 1995;6(1): 226-230. |
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THROMBOLYTIC THERAPY IN ACUTE MYOCARDIAL INFARCTION
: EFFECT ON RESIDUAL MYOCARDIAL ISCHEMIA AND CARDIAC EVENT
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| Jun Hee Lee, Kyung Rae Kim |
| Department of Emergency Medicine, College of Medicine, Inha University |
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Published online: June 30, 1995. |
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| ABSTRACT |
Background
Thrombolytic therapy was known as first treatment of choice in patients with acute myocardial infarction(AMI). This study was designed to assess the effect on residual ischemia and cardiac event (postinfarct angina, recurrent myocardial infarction, cardiac death) after thrombolytic therapy for AMI.
Method and Results : We reviewed 42 patients, admitted with AMI during three years from January 1991 to December 1993. all patients performed treadmill test or thallium scintigraphy and had out-patient follow-up checking over one year. Twenty one patients were recieved by thrombolytic therapy (Group A) and the remaining twenty one patients were not (Group B). Mean age was 58 土8 years in group A and 60 士11 years in group B. Residual ischemia was reduced by thrombolytic therapy, 19% in group A compared with 48% in group B (P<0.05). No significant differences in incidence of cardiac event were found between the two groups(19% and 19%).
Conclusion
Thrombolytic therapy reduced the residual ischemia after AMI but did not re duced the incidence of cardiac event in long term follow-up.
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| Key words:
Acute myocardial infarction, Thrombolytic therapy, Residual ischemia, Cardiac event |
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