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Journal of The Korean Society of Emergency Medicine 1996;7(2): 188-194. |
| USEFULNESS OF TROP-T® RAPID ASSAY FOR EARLY DETECTION OF MYOCARDIAL INFARCTION IN PATIENTS PRESENTING
WITH ACUTE CHEST PAIN
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| Hyun Jyung Kim, Jun Young Chung, Chang Hyun Lee, Ho Suk Doh, Sam Beom Lee, Byung Soo Do |
| Department of Emergency Medicine, Yeungnam University college of medicine |
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Published online: June 30, 1996. |
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| ABSTRACT |
Study objectives : In the past, measurement of cardiac enzymes (i.e. CK and/or CK-MB, GOT, LDH) and myoglobin, cardiac specific serum troponin-T were widely used for the diagnosis of acute myocardial infarction, but it need a long time and have low specificity. Thus new diagnostic modality, TROP-T® Rapid Assay, is very easy and rapid qualitative methods, is needed for the early detection of acute myocardial infarction.
Method
: Total CK, GOT, LDH, myoglobin and serum troponin-T activities were measured in patients presenting with acute chest pain at the emergency department and at the same time TROP-T® Rapid Assay was done. Final diagnosis and diagnostic usefulness was evaluated
Results
: Overall diagnotic sensitivity and specificity of initial results were as follows; TROP-T®
Rapid Assay, 77.3, 100.0; myoglobin, 63.6, 70.4; CK, 95.5, 96.3; GOT, 86.4, 96.3; LDH, 90.9, 92.6; serum
troponin-T, 86.4, 96.3, respectively.
Conclusion
The TROP-T® Rapid Assay is simple method and has a short time and nearly same sensitivity and specificity compared to other cardiac enzymes. Thus this is considered useful method in the early detection of acute myocardial infarction at emergency department.
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| Key words:
TROP-T® Rapid Assay, Acute myocarclial infarction |
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