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J Korean Soc Emerg Med > Volume 7(4); 1996 > Article
Journal of The Korean Society of Emergency Medicine 1996;7(4): 449-457.
THE EFFECT OF 100% OXYGEN ON THE OXYGENATION OF GUT MUCOSA IN HEMORRHAGED CATS
Yu Mee Lee, Kyung Don Hahm
Department of Anesthesiology, Asan Medical Center, Seoul, Korea
  Published online: December 31, 1996.
ABSTRACT
Background
This study was purposed to study the effect of 100% oxygen on the oxygenation of gut mucosa in a feline model subjected to a hemorrhagic shock followed by reperfusion.
Method
: Eighteen cats were divided into three groups : For group I, 6 cats were subjected to sham operation as a control group ; for group II, 6 cats were subjected to a hemorrhagic shock for 2 hours prior to reperfusion and ventilated with air as a medical air group ; for group III, 6 cats were ventilated with 100% oxygen, continued during the shock and reperfusion periods as a 100% oxygen group. Mesenteric PvO2, mesenteric PaO2, mesenteric venous arterial(v-a) lactate difference, mesenteric P(v-a)CC}z and mesenteric pH(a-v) were measured for every 30 minutes during the shock and reperfusion.
Results
: For group II and group III, the lactate(v-a) was increased during the shock. The values of pH(a-v) and P(v-a)COz were increased during the shock but not returned to the baseline value after reperfusion. For both pH(a-v) and P(va)CO2, there were not statistically significant differences between group II and group III during the shock and reperfusion. For group III, the PaO2 was increase during the shock and reperfusion, there were statistically significant differences(p<0.05) between group II and control, and between group III and control.
Conclusions
: We conclude that the 100% oxygen does not improve the oxygenation of gut mucosa in the feline model undergone a hemorrhagic shock followed by reperfusion.
Key words: Shock; Hemorrhagic, Oxygen, Intestinal mucosa.
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