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Journal of The Korean Society of Emergency Medicine 2009;20(4): 422-427. |
| A Comparison Study of Two Different Methods of Administration: Intranasal versus Intramuscular for Pediatric Procedural Sedation and Analgesia |
| Kyoung Chan An, Jung Hwan Ahn, Kug Jong Lee, Yoon Seok Jung, Sang Cheon Choi, Young Shin Cho, Ji Sook Lee, Choung Ah Lee, Gi Woon Kim |
1Department of Emergency Medicine, Ajou University School of Medicine, Korea. flyingguy@ajou.ac.kr
2Member of Society for Clinical Procedures and education, Korea. |
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| ABSTRACT |
PURPOSE:
To compare the efficacy of ketamine between intranasal (IN) administration and intramuscular (IM) injection for pediatric procedural sedation and analgesia (PPSA).
METHODS:
A prospective study was conducted during 3 months.
Ketamine was given by IN or IM route before primary repair of facial laceration for procedural sedation. The administration dose was 8 mg/kg for IN and 4 mg/kg for IM.
We evaluated resistance scale on administration, sedation scale, satisfaction of physician and parents.
RESULTS:
One hundred children were enrolled into this study.
IN administration was given to 50 children, and IM injection to 50 children each. In the IN group, 75%(36 of 50) showed severe resistance, whereas only 34%(17 of 50) showed severe resistance and 50%(25 of 50) showed mild resistance in IM group. Successful rate of sedation after initial administration was 82%(41 of 50) in IM group and 34% in IN group. Satisfaction of physicians and parents was high in IM injection group.
CONCLUSION:
Intranasal administration of Ketamine is less effective and provides lower satisfaction than intramuscular injection for procedural sedation of pediatric patients in the emergency department. |
| Key words:
Intranasal Administration, Intramuscular Injection, Ketamine, Conscious Sedation |
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