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Journal of The Korean Society of Emergency Medicine 2005;16(4): 486-489. |
| Case of a Soleus Muscle Hematoma with Compartment Syndrome Complicated by Enoxaparin and Aspirin Therapy |
| Dong Wook Choi, Yong Hoon Kim, Sang Wook Kim, Ae Young Her, Soo Ik Awe, Jun Hwi Cho |
1Department of Internal Medicine, College of Medicine, Kangwon National University, Chuncheon, Korea. yhkim02@kangwon.ac.kr
2Department of Orthopedic Surgery, College of Medicine, Kangwon National University, Chuncheon, Korea.
3Department of Emergency Medicine, College of Medicine, Kangwon National University, Chuncheon, Korea. |
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| ABSTRACT |
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Enoxaparin is a low-molecular-weight heparin that has been widely used in acute coronary syndrome patients. The tolerability profile of enoxaparin is at least similar to that of unfractionated heparin, but the incidences of local hematomas and increased liver enzymes are lower. We experienced one case of enoxaparin-associated soleus muscle hematoma with compartment syndrome. An 83 year-old woman received enoxaparin (1 mg/kg q 12 hours) and oral aspirin (100 mg qd) therapy due to a non-ST elevation myocardial infarction. On the 3rd hospital day, she complained of pain and a tingling sensation in her left calf muscle. A left lower leg CT scan showed a 5.1 x 2.3 x 1.5 cm hematoma compressing the left soleus muscle. An Emergency operation was done to extract the large hematoma. Whenever acute symptoms, including leg pain, tingling sensation, and anemia occur during anticoagulation therapy, the possibility of enoxaparin-associated hematoma should be considered. |
| Key words:
Low-molecular-weight heparin, Enoxaparin, Hematoma, Compartment syndrome |
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