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J Korean Soc Emerg Med > Volume 31(4); 2020 > Article
Journal of The Korean Society of Emergency Medicine 2020;31(4): 362-370.
단일 응급의료센터에서의 propafenone 정주제제 사용에 대한 경험
정용욱 , 하상욱
한림대학교 의과대학 성심병원 응급의학과
Experience of administration of intravenous propafenone in single emergency medical center
Yongwook Jung , Sang-Ook Ha
Department of Emergency Medicine, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea
Correspondence  Sang-Ook Ha ,Tel: 031-380-4138, Fax: 031-380-4131, Email: mdhso@hallym.or.kr,
Received: July 12, 2019; Revised: August 29, 2019   Accepted: September 4, 2019.  Published online: August 31, 2020.
ABSTRACT
Objective:
We aimed to share our experience studying the effects and stability of intravenous propafenone in patients with atrial fibrillation (AF).
Method:
This single-center retrospective study evaluated the baseline and clinical characteristics of patients with atrial fibrillation admitted to the emergency room and treated with propafenone between December 2018 and May 2019; patients were analyzed according to new onset AF and chronic AF groups.
Results:
Among 24 patients included in the present study, 15 patients were in the new onset AF group while nine were in the chronic AF group. Cardioversion was successful in 15 (73.3%) in the new onset AF group and two (22.2%) in the chronic AF group (P=0.033). The time to cardioversion was relatively short in patients in the new onset AF group (81 minutes vs. 122 minutes, log-rank, P=0.019). Recurrence of AF at 30 days was two (17.2%) in the new onset AF group and 0 (0.0%) in the chronic AF group. No major adverse event was observed except each hypotension in the new onset and chronic AF groups.
Conclusion:
Sinus conversion of propafenone in patients with AF occurring within 48 hours in the emergency room may be considered.
Key words: Atrial fibrillation; Anti-arrhythmia agents; Propafenone
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